Two common steps in cell therapy manufacturing, cell harvest and cell washing, can damage cells if they are exposed to high shear forces. This can lead to a decrease in the number of viable cells, which can impact the efficacy of the therapy. The CARR Biosystems UniFuge family of centrifuges is a valuable tool for cell therapy manufacturers who are looking to improve the viability and recovery of their cells.
Review data that demonstrates the performance of a single-use centrifuge for the harvest of cells in cell therapy production. Specifically, the key performance indicators of cell viability and cell recovery are presented for a variety of common cell types and over a range of processing conditions, such as feed flow rate and g-force.