Cancer Immunotherapy: Engineered Immune Cells For Anti-Tumor Immunity

Immunotherapy is a rapidly expanding form of cancer medicine, focusing on enhancing the body's immune response to combat cellular malignancies. One approach, known as cell-based immunotherapy, involves the adoptive transfer of tumor-targeting cytotoxic immune cells, with or without gene modification, to neutralize tumors. Treatments utilizing gene-engineered T cells that target tumor antigens, natural killer (NK) cells, and other unconventional immune cells like invariant natural killer T cells (iNKT) and γδ T cells have shown promise in addressing various malignant tumors. This poster presents a comprehensive overview of cell-based cancer immunotherapy, highlighting the techniques for engineering immune cells and the methods used for manufacturing genetically modified cells that are currently in use.