Bringing Automation Into Process Development Early

In this segment of our Cell & Gene Live, Automating Autologous CAR T Manufacturing: Lessons from Mayo Clinic, expert panelists Anthony DeFusco, M.S., Senior Director of Quality Control for the Center for Regenerative Biotherapeutics; Snigdha Rai, M.S., Senior Director of Biomanufacturing; and Cynthia Wilkins, Ph.D., M.B.A., Senior Director of Process Development and Assistant Professor of Regenerative Medicine, Mayo Clinic examined when developers should begin planning for automation and why waiting until a manual process is optimized can lead to costly redesigns. They discussed how automation can improve consistency, reduce operator variability, and potentially reduce sampling when supported by process understanding, reliable sensors, and a validated control strategy.