Product/Service

Benchtop Macro Mass Photometer: KaritroMP

Source: Refeyn
KaritroMP

The new KaritroMP is a benchtop instrument that characterizes large viral vectors. Ideal for informing process development in preclinical settings and early drug development, it analyzes samples of adenovirus vectors (AdV) and lentivirus vectors (LVV) in just minutes. The instrument offers essential vector analysis capabilities, including the assessment of sample purity and stability.

Using novel macro mass photometry technology, this pioneering tool performs single-particle analysis, enabling users to visualize distributions of viral particle populations within their samples. It can resolve distinct populations of vectors and reveal changes over time – indicating whether a sample is suitable for further processing and helping users save time and resources.

  • Fast, simple, qualitative AdV and LVV analysis

  • Differentiation of multiple populations, even those of the same size

  • Evaluation of relative changes across samples, from crude to purified

Vital insights into viral vector samples​​

  • Empty/full measurement for AdV

  • Analysis of purity and stability for AdV and LVV

Rapid, user-friendly operation​​

  • 6 minutes per sample

  • Little sample needed (5 μL at 1E8 – 1E9 particles/mL)

  • Minimal sample preparation

  • Benchtop instrument

Essential capabilities​ for process development and optimization

  • Compare production or purification methods

  • Identify batch-to-batch variations