Automated DNA Size Selection For Flexible NGS Workflow Integration

Automated size selection is a critical step in preparing high‑quality NGS libraries, and this resource highlights a streamlined approach that delivers accuracy, consistency, and cost efficiency. It walks through single‑sided and double‑sided magnetic‑bead size selection, showing how controlled bead ratios enable reliable removal of unwanted fragments while preserving target material. Detailed protocols illustrate how automated liquid handling and programmable magnet positioning help reduce hands‑on time, minimize variability, and support high‑throughput workflows. Performance comparisons demonstrate that the featured bead chemistry produces fragment recovery and size‑selection precision on par with established industry reagents, even when processing dozens of replicates.

Gain practical insight into optimizing bead ratios, pipetting strategies, and magnet height adjustments to meet diverse library prep needs.