Advancing Viral Vector Manufacturing With Innovation: The Importance Of The Cell Line.
Optimizing suspension cell-culture methods for viral vector manufacturing requires careful consideration of several critical parameters, including the target vector or therapeutic use, which determines the necessary production scale. Utilizing high-quality media, transfection reagents, cell lines, plasmids, and other resources is also essential.
In this webinar, our experts will emphasize the significance of the cell line in viral vector manufacturing—a multi-step process that has traditionally been time-consuming and labor-intensive. They will focus on the generation and subcloning of the serum-free suspension HEK293-SKPT-4G9 cell line, a leading candidate in this field. Additionally, the webinar will cover transfection optimization through Design of Experiments (DoE), virus characterization, and provide an overview of virus production capabilities for AAV, lentivirus, and adenovirus.
Learning points from the webinar:
- Discover innovative cell line development for AAV, LV, and adenovirus production.
- Understand the creation of a high-performing, monoclonal suspension HEK293 cell line for CGMP cell banking.
- Compare our cell line with industry standards.
- Visualize the cost savings achieved with an optimized manufacturing cell line.
- Explore next steps and future advancements in viral packaging cell line evaluation to enhance processes and platforms for cell and gene therapies.
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