Newsletter | November 4, 2025

11.04.25 -- STREAM Edition: Advancing Gene Therapy For FTD

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Webinar: Accelerate your pDNA and mRNA process development

Discover how to achieve high-yield plasmid DNA (pDNA) production in this Cytiva webinar. The Fast Trak™ team shares a systematic approach to developing and scaling a pDNA process using E. coli OneShot Top10. Learn how design of experiments (DOE), optimized culture conditions, and the Xcellerex™ XDR-50 fermentor enable seamless scale-up from benchtop to pilot scale while maintaining yield, quality, and process control. Click here to learn more.

Assessing Residuals In Processing And Fill/Finish For iPSCs

Video | Cell & Gene

In this segment of Cell & Gene Live, Optimizing Storage Solutions for iPSCs, our expert panelists explain why detecting and quantifying trace levels of cryoprotectants and excipients involves a risk-based approach based on formulation concentrations and patient exposure limits.

Automating Ancillary Processes: Closing Bottlenecks In CGT Manufacturing

Webinar | Invetech

Watch as speakers share a variety of real-world challenges encountered when closing and automating ancillary processes, and how implementing closed automated platforms significantly improved scalability, reproducibility, and overall efficiency.

The CDMO Value Proposition For Your Autologous Cell Therapy

Webinar | Lonza

Kelly Kral, VP, CMC Strategy & Operations, bluebird bio, and Anthony Basile, Account Management CGT, Lonza, share a decade-long story of partnership in bringing two life-changing gene therapies to market. Dive deep into the CDMO value proposition for autologous cell therapy.

Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup

Video | Aliri Bioanalysis

By leveraging this innovative combination of technologies, the assay achieves detection limits comparable to traditional methodologies, while significantly enhancing overall efficiency, reliability, and operational consistency of implementation

Andelyn Biosciences Capacity Update: Cell & Gene Therapy

Video | Andelyn Biosciences

Here we introduce the structure and capabilities of our Laboratory Services group, a cornerstone of our commitment to excellence, innovation, and quality in pharmaceutical development, analytical testing, and technical support.

Development Of A CHO Medium And Feed System

Webinar | Thermo Fisher Scientific Bioproduction

Discover how a new, chemically defined cell culture medium and feed system can maximize recombinant protein production in Chinese hamster ovary (CHO) cells, enhancing productivity and streamlining manufacturing.

Advancing Gene Therapy For FTD With Passage Bio's Dr. Will Chou

Video | Cell & Gene

In this episode of Cell & Gene: The Podcast, Host Erin Harris talks to Will Chou, M.D., CEO of Passage Bio about the promise and challenges of developing gene therapies for frontotemporal dementia (FTD), a neurodegenerative disease with strong genetic underpinnings.

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Join Jon O'Connell and experts on this Cell & Gene Live event, exploring whether minimum viability can help gene therapy developers make smarter sourcing decisions — from research-grade production through clinical and commercial phases, where cost and quality can make or break a product. Registration is free with support from Roche CustomBiotech.