Newsletter | July 3, 2025

07.03.25 -- Advancing Gene Delivery: LNPs, Adenovirus, Lentivirus, And More

SPONSOR

Explore the evolving role of exosomes and extracellular vesicles (EVs) at the next Cell & Gene Live. Chief Editor Erin Harris moderates a discussion with Capricor’s Linda Marbán and Aegle’s Dr. Gloria Matthews on clinical and commercial advances, including applications in rare and cardiovascular diseases. Gain insights into the future of exosome-based therapies from leaders driving innovation across R&D, manufacturing, and commercialization.

FOCUS ON MANUFACTURING

Advancing Gene Delivery: LNPs, Adenovirus, Lentivirus, And More

During this month’s Cell and Gene Live, Advancing Gene Delivery: LNPs, Adenovirus, Lentivirus, And More, expert panelists Francesca Barone, M.D., Ph.D., CSO at Candel Therapeutics and Karen Kozarsky, Ph.D., President of Vector BioPartners shared their perspectives on current challenges, technological innovations, and future directions in gene therapy vector development and application.

Innovations In CGT Processing

Discover insights into how innovative connectors streamline workflows, save time, and enhance reliability in critical applications, ultimately supporting improved outcomes in cell and gene therapies.

Optimize Advanced Therapy Manufacturing Process Before You Automate

Dive into specific unit operations and case studies that demonstrate how implementing phase appropriate tools can have substantive direct business impacts to cost and development timelines.

Solutions For The Clinical-Grade Manufacturing

Explore the crucial role of NK cells in the immune system and learn efficient methodologies for manufacturing gene-engineered NK cells and scaling up production.

mRNA Vaccines And Therapeutics: Current Trends And Perspectives

Delve into the advancements and transformative impact of mRNA vaccine technology on modern medicine and explore how this technology is revolutionizing healthcare for the future and beyond.

Double, Double, Experts Huddle, Cells And Bioprocess Bubble

Biomanufacturing leaders unite to optimize exosome/EV production. Explore their combined upstream/downstream approach for optimized cell culture, purification, and quality control.

Comparison To And Advantages Over Traditional Chemometrics Models

As Raman spectroscopy, with partial least squares (PLS) models, becomes more popular in bioprocesses applications it's important to recognize the challenges this approach presents.

Optimizing AAV Purification For High Recovery

How can you improve purification methods for your AAVs and enhance the efficacy and safety of your gene therapy treatments?

Key Factors For Successful Plasmid Production

Review the distinct steps in the plasmid production workflow, along with tips for optimization from vector and strain selection to cultivation and beyond.

Considerations For Cell Therapy Development And Manufacturing

Review the latest methodologies, common practices, resources, applications and more to support every step of your cell therapy manufacturing workflow.

SPONSOR

Webinar: Improving Quality Control: Tackling Residual DNA Testing in Biotherapy Manufacturing

Explore how to strengthen quality control in biotherapy manufacturing with advanced residual DNA testing in this webinar from Thermo Fisher Scientific. Learn why residual DNA testing is vital for product safety and compliance, uncover common challenges and misconceptions, and discover how molecular-based methods can enhance accuracy, sensitivity, and reliability in your QC workflows. Click here to learn more.

MANUFACTURING SOLUTIONS

A Single Resource For Total Cleanroom Confidence - AES Cleanroom Technology

Say "Hello" To The PBS Vertical-Wheel Bioreactors - PBS Biotech, Inc.

From Concept To Creation: An Inside Look At Engineering Design - Germfree

Optimize Your RNA-LNP Delivery With Ionizable Lipids - Cytiva

Vial Adapter Considerations For CGT Applications - West Pharmaceutical Services, Inc.

Connect With Cell & Gene: