Advanced Technologies
Source: Forge Biologics
At Forge, our platform approach employs the triple plasmid transfection method – the industry standard method for manufacturing AAV. This method is bolstered by Forge’s proprietary technologies, our Ignition Cells™ and pEMBR™ adenovirus helper plasmid.
Ignition Cells™
- Royalty-free license for clients
- Clonal HEK293 mammalian suspension cell line
- Optimized for robust transient transfection
- Animal component free
- Scalable production
pEMBR™ Adenovirus Helper Plasmid
- Lower cost for production
- Improved safety profile – removed unnecessary adenoviral elements
- Forge Biologics intellectual property
- Available for pipeline use
pEMBR Design Features
pEMBR Yield Comparison
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