A Guide To mRNA Vaccine Production And Manufacturing Services

Polyplus outlines the key steps for successful mRNA vaccine production, which encompasses mRNA manufacturing using their plasmid engineering services and LNP formulation process with their novel LipidBrick^® IM21.7c cationic lipids optimized for mRNA delivery.

The overall positive charge imparted by the LipidBrick IM21.7c to the formulated LNP enables a wider in vivo biodistribution and reduce liver accumulation. This can improve drug potency, safety, tissue targeting, and formulation stability compared to current generation cationic lipids