Insights on Discovery
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Scaling Up mAb Process Development To A 5L Bioreactor
4/10/2024
This study, conducted with cloud-connected bioreactors designed to accommodate CHO cells, showcases this technology transfer by comparing results obtained from shake flask cultures at various scales.
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Designing The Human Emulation System
4/9/2024
Examine how the Human Emulation System merges cutting-edge Organ-on-a-Chip technology with user-friendly design, paving the way for seamless experimentation and deeper insights into human biology.
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Evaluating On-Target/Off-Tumor Effects Of Cancer Immunotherapies
4/9/2024
A promising class of engineered T-cell engaging bispecific antibodies (TCBs) is revolutionizing cancer treatment, but safety concerns persist. Organs-on-Chips offer a human-relevant solution.
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Exploring Neuroinflammation, Neurodegeneration With A Brain Organ-Chip
4/9/2024
Examine how Organ-on-a-Chip technology, accurately mimicking human neuroinflammation, offers promising human-relevant avenues for neurodegenerative disease research and therapeutic development.
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Studying Gut Inflammation And Barrier Disruption With Organ-On-A-Chip Technology
4/9/2024
See how the Colon Intestine-Chip has been employed to model cytokine-mediated inflammation and barrier disruption in the intestine.
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Recapitulating Inflammation: How To Use the Colon Intestine-Chip To Study Complex Mechanisms Of IBD
4/9/2024
To address the challenges associated with conventional drug development models, a Colon Intestine-Chip has been developed to recapitulate the biology that drives inflammatory bowel disease.
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Predicting Human Liver Damage With A More Accurate In Vitro Hepatotoxicity Assay
4/9/2024
This study explores whether a species-specific, multicellular, in vitro hepatotoxicity assays utilizing Liver-Chips can provide a greater understanding of hepatotoxicity mechanisms than animal models.
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Investigating Key Mechanisms Of Parkinson’s With A Novel Model
4/9/2024
Efforts to develop a dynamic “brain-on-a-chip” model that closely resembles the human substantia nigra could be applied to study mechanisms of Parkinson’s disease.
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Creating A Shigella Infection Model Using Organs-On-Chips
4/9/2024
Learn how researchers have utilized Organs-on-Chips technology to test the infectivity of Shigella through several experimental approaches.
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Developing More Clinically Relevant Drug-Induced Thrombosis Models
4/9/2024
Learn how this Blood Vessel-Chip is capable of replicating drug side effects and mimicking the human circulatory system accurately, enhancing drug safety and efficacy in development.