Understanding Cryopreservation Of Cellular Therapies

Cryopreservation is the process of using ultra-low temperatures to preserve living cells and tissues for a prolonged time period.

In a typical immunotherapy commercial manufacturing workflow, cells may be selectively isolated from peripheral blood or tumour tissues, genetically engineered, activated and expanded to relevant doses, harvested, packaged and cryopreserved, before transporting the final cellular product to the site of clinical administration. At the clinical site, the cryopreserved cells are eventually thawed and infused into patients awaiting treatment.