Article
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By Vanee Pho-Conners,
Mission Bio
Explore some of the major challenges in the cell and gene therapy world and how single-cell multi-omics analysis can overcome many of these issues.
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Article
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By Josh Russell,
AST
The aim of advanced aseptic processing is the elimination and absolute control of all sources of contamination – most importantly, human generated contamination. Robotics and isolator barrier systems are core technologies in this endeavor.
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Article
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By Stefan Randl and Maaike Everts,
Evonik Corporation
Discover how mRNA technologies open the doors to a whole range of new gene therapies and the role of lipid nanoparticles (LNPs) in current and future developments.
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White Paper
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By Mark Jones, Annie Cunningham, Nathan Frank, and Dalip Sethi,
Terumo BCT
Explore an eight-day expansion of a 2 × 10 positively selected CD34+ cell inoculum from three donor lineages and the results proving the automated monoculture protocol can support that expansion with minimal lymphocyte residual.
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White Paper
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By Wolfram Schulze,
Rentschler Biopharma
The fourth industrial revolution is coming. Explore the three essentials of bioprocess development and manufacturing digitalization: digital literacy, digital trust, and prioritization.
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Application Note
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By Craig Tamble and Nadia Kadi,
Pall Corporation
This study assesses the use of NAB Nanosep centrifugal devices with commercially available reagents for PCR or agarose gel cleanup.
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Poster
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By Ian Scanlon, Ben Wallis, Adam Pinnock, Nathaniel Hughes, Eric Schmid, Marc Hummersone, and Bilal Ahmad,
Astrea Bioseparations
We demonstrate a novel composite nanofiber material that can bring fast flow rates and increased binding capacities to biological product purification.
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Article
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Precision NanoSystems
There are two key challenges to realizing the potential of genomic medicines, but potential technological solutions are on the horizon, and we examine each.
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Article
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Berkeley Lights
The Opto Cell Line Development workflow on the Beacon system has been demonstrated to provide >99% probability of clonality from a single automated round of cloning. Here's the three-part process.
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Article
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OmniaBio
Learn about some of the current issues impacting the manufacture and supply of cell and gene therapy products, including manufacturing and shipping costs, upscaling, and pandemic-related issues.
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Article
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Minaris Regenerative Medicine
For development into late-stage and commercial production, constraints arise that limit using “fresh” final products. So, cryopreservation of the final product becomes an option and, in some cases, even a necessity.
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Article
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AcuraBio
Defining a scope of work with a CDMO to deliver pDNA material for needed clinical supply requires careful consideration to meet the requirements of the regulatory body.
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Case Study
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Advanced Instruments, Inc.
We explore how the cell line development group at Janssen R&D was able to reduce one of their development processes to a single step thanks to new technology.
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e-book
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Waters Corporation
This notebook compiles several recent application notes generated by the Biopharmaceutical Scientific Operations Team at Waters. They illustrate key attribute monitoring workflows that have been developed to improve and streamline MAM analysis of biotherapeutic proteins.
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Q&A
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W.L. Gore & Associates
Learn more about a flexible freeze container that maintains package integrity after freezing at minus 86 °C. (minus 123 °F) and minimizes product loss due to package failure due to its durable design.
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Webinar
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Entegris, Inc.
This webinar focuses on how filtration manufacturers optimize materials for performance and integration within single-use systems.
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Webinar
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Project Farma
In this webinar, learn tips from a panel of industry experts for delivering efficient, reliable, GMP-compliant facilities and processes specific to cell therapy.
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Webinar
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Aldevron
Discover key upstream and downstream considerations for process development for RNA drug substance manufacturing and the parameters that need construct-specific optimization to increase yield and reduce impurities.
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