Fluoropolymer Material Advantages In Biomanufacturing
By Julien Muzard, Joy Chen, Muhammad Siddiqui, and Ross Acucena, Entegris
Disposable solutions are now widely accepted as the gold standard in the biopharmaceutical industry covering every single step of drug manufacturing. From early-stage small scale R&D projects, upstream production with several thousand-liter bioreactors, downstream process, API formulation up to critical fill/finish and transport applications, the industry is shifting from traditional processes to take advantage of single-use technology benefits.
Entegris' commercially available gamma stable, fluoropolymer film has been used to support various applications such as large-scale bioprocessing/banking of mammalian cells (intensification), bulk drug substance (BOS), cell and gene therapy (adenovirus), critical vaccinology program (mRNA LNP/liposomes), as well as protein-based therapeutics at large, industrial scales worldwide.
In this poster we review how the Aramus™ Fluoropolymer Bag performs in various temperatures, the frozen drop performance, chemical compatibility. Discover how fluoropolymer is bypassing traditional biomanufacturing and disposable multilayered films.
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