01.19.23 -- Explore Biophysical Characterization Of A Therapeutic mAb

Executives from Moderna, Sanofi Pasteur, Takeda, and Catalent shared behind-the-scenes information on their respective efforts to develop a COVID-19 vaccine. With different approaches, the companies all adopted a collaborative mindset to arrive at a vaccine as quickly and safely as possible.

In this webinar, explore how to quickly transition your product from prefilled syringe to auto-injector with an experienced partner who can anticipate equipment and process needs.

Four experts share how scale-up, regulatory expectations, demand forecasting, and process validation all play a role in the success of a biologic when embarking upon the commercial manufacturing journey.

Determining size homogeneity of a mAb in solution is important for comparability and characterization. For this study, an IgG1 antibody was cleaved into antigen-binding fragments using pepsin and papain digestion respectively, followed by Protein A purification.