Expand And Rapidly Validate Antigen-Specific Function Of T Cells With Fewer Cells

Immunogenicity validation is a critical bottleneck in the tumor antigen discovery process in part because the vast majority of candidate neoantigens identified in a tumor are not recognized by T cells.  The Opto™ Antigen Presenting Bead Kit used with functional assays in the Opto Cell Therapy Development workflow addresses this bottleneck by enabling you to:

• Remove variability in antigen presentation
• Validate peptide-HLA binding and stability before initiating costly cell stimulations
• Expand rare (0.001%) antigen-specific T cells from healthy donor blood 10-fold more efficiently than using DCs while saving time, labor, and cells by avoiding dendritic cell differentiation
• Validate antigen-specific T cell function using fewer cells, saving time, labor, and avoiding bulk expansion

Watch this 10-minute product tour to see how.