CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• DNA Purification From PCR Or Agarose Gels

  This study assesses the use of NAB Nanosep centrifugal devices with commercially available reagents for PCR or agarose gel cleanup.

• Capsules Versus Hollow Fibers For Ultrafiltration/Diafiltration (UF/DF)

  Explore the performance evaluation of a first-of-its-kind spiral-wound TFF filter versus hollow fibers for UF/DF of viral vectors and the impact of either filter type on a TFF process.

• Achieve Fast And Efficient Isolation Of Exosomes From Stem Cells

  Review this demonstration of a bioreactor and bioreactor system combination used to isolate exosomes after culturing human adipose-derived stem cells in suspension on microcarriers.

• Primary Clarification Of Lentiviral Vector With Low-Shear Separation

  Evaluate the performance of a cell harvesting system using data on the titer recovery and turbidity during the downstream processing and clarification of lentiviral vectors.

• A Perspective On Various Use Cases Of Osmolality In Quality Control

  Learn how osmolality testing provides quick and easy identification of where certain solutions may be deviating from specification in the biomanufacturing sector of the clinical market.

• Expansion Of MDCK Cells On Microcarriers Via Growth In Stirred Vessels

  We demonstrate how microcarriers provide an ideal substrate for expansion of MDCK cells in closed stirred-vessel systems and lay the groundwork for subsequent developmental studies in larger bioreactor formats.

• Revolutionizing Viral Infectious Disease Research And Drug Discovery

  Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.

• Biosafety Testing And Quality Control Requirements For Lentiviral Vectors

  Learn more about manufacturing principles of LV vectors as well as testing requirement regulatory considerations with a particular focus on the replication competent virus assay and infectious titer assay.

• GMP-Validated Adventitious Virus Testing By Next Generation Sequencing

  Gain required knowledge related to the involved regulatory authorities and scientific technologies and disciplines: Next Generation Sequencing (NGS), Bioinformatics and Computer System Validation (CSV).

• Decentralized Trials For Duchenne Muscular Dystrophy

  Partnering with a global biotech, see how MRN was able to conduct 180+ monthly home visits to sustain trials for rare disease genetic medicine in vulnerable pediatric patients during COVID-19.